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TPA Inc
TPA Inc
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    • Home
    • About Us
    • Our Team
    • Services
      • Gross Pathology
      • Histology
      • Pathologist Services
      • Molecular Pathology
      • Clinical Pathology
      • Special Procedures
      • Data Management
      • Digital Imaging\Analysis
      • Quality Assurance
    • News
      • News
      • Recent Presentations
      • Recent Publications
    • Explore Arkansas
    • Join our Team!
    • Contact Us

  • Home
  • About Us
  • Our Team
  • Services
    • Gross Pathology
    • Histology
    • Pathologist Services
    • Molecular Pathology
    • Clinical Pathology
    • Special Procedures
    • Data Management
    • Digital Imaging\Analysis
    • Quality Assurance
  • News
    • News
    • Recent Presentations
    • Recent Publications
  • Explore Arkansas
  • Join our Team!
  • Contact Us

Innovative Techniques

Gastro Intestinal pH

Gastro Intestinal pH

Gastro Intestinal pH

TPA provides in vivo measurement of the pH of the gastro intestinal tract.

Tissue Organoids

Gastro Intestinal pH

Gastro Intestinal pH

TPA provides custom processing of 1-2 mm tissue organoids for paraffin embedding, sectioning and immunostaining.

EDTA Decalcification

EDTA Decalcification

EDTA Decalcification

Non-routine bone decalcification with EDTA allows for immunostaining of bone tissue section with improved morphology over acid decalcification.

Glycol methacrylate

EDTA Decalcification

EDTA Decalcification

Glycol methacrylate (GMA) processing, embedding, sectioning and staining is used for ultra-thin (1-2 µ) tissue sections.

Osmification of Tissues for Lipid evaluation

Hematoxylin and Eosin Stained

Hematoxylin and Eosin Stained

Hematoxylin and Eosin Stained

Arrows show Cytoplasmic Vacuols

The arrows show cytoplasmic vacuols.

Osmium Tetraoxide Stained

Hematoxylin and Eosin Stained

Hematoxylin and Eosin Stained

Arrows show osmium tetraoxide stained fat droplets.

The arrows show osmium tetraoxide stained fat droplets.

Organoids

Rat Testicular Organoids

Recently a 3D culture has been developed that allows the reorganization of rat primary testicular cells into organoids with a functioning blood-testis barrier, as well as the establishment and maintenance of germ cells. This technique is successfully used by NCTR investigators. TPA provides support for histological evaluation as well as immunohistochemical identification of types of cells and structures in the organoids.

Rat testicular organoid (H&E), x4

Rat testicular organoid (H&E), x4

ZebraFish Diagnostic Evaluation

Gross Photography

Spinal Cord Gram Stain 40X

Spinal Cord H&E Stain 40x

A curved spine is a clinical sign of Microsporidiosis (xenomas).

Spinal Cord H&E Stain 40x

Spinal Cord Gram Stain 40X

Spinal Cord H&E Stain 40x

The arrow shows Microsporidiosis (xenomas) in the spinal cord of a ZebraFish.

Spinal Cord Gram Stain 40X

Spinal Cord Gram Stain 40X

Spinal Cord Gram Stain 40X

 The arrow shows Microsporidiosis (xenomas) in the spinal cord of a ZebraFish. 

Solvent Recycling

TPA has a number of distillation units in use to recycling xylene, alcohol, methanol, formalin and acetone. This not only saves on the initial reagent purchases, but also saves time, waste disposal costs; also obviating the need to store large volumes of hazardous chemicals before use and disposal. 

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